Turning environmental data into real-world impact across Colorado and Wyoming

The ASCEND Engine’s strategy (2026–2029) for accelerating discovery, innovation, and workforce development across the Colorado-Wyoming I-25 Innovation Corridor

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Building an integrated innovation ecosystem

The ASCEND Engine is building an ecosystem that connects researchers, entrepreneurs, communities, and policymakers capable of sustained innovation and impact across the region.

Over the next three years (2026–2029), the ASCEND Engine will transition from establishing foundational partnerships, research programs, and infrastructure to delivering integrated, scalable solutions for environmental resilience along the Colorado–Wyoming I-25 Innovation Corridor.

We will focus on:
  • Building a resilient ecosystem that connects researchers, entrepreneurs, communities, businesses, and policymakers.
  • Launching large-scale, cross-disciplinary programs that integrate sensing, analytics, and decision tools.
  • Strengthening pathways from discovery to deployment to achieve real-world impact.
  • Developing the next generation of innovation talent through education, training, and entrepreneurship programs anchored in the Colorado–Wyoming I-25 Innovation Corridor.

MOONSHOT PRIZE

In 2027, we will launch a large-scale Moonshot Prize focusing on the soil health measurement scalability challenge. The prize will be a competitive, global competition and will be run in partnership with XPRIZE.

The ASCEND Engine’s technical focus

Unlike traditional research programs, the NSF ASCEND Engine’s strategy is intentionally integrated. Each Technical Area is designed to reinforce the others — sensing feeds analytics, analytics informs decisions, and decisions reveal new questions for sensing — enabling outcomes no single area could achieve alone.

Advanced Sensing and Data Generation
Capturing the world as it is
We will invest in next‑generation sensing technologies — from soil‑level measurements to satellite observations to quantum sensing technologies — that generate high‑resolution, real‑time environmental data.
Focus areas include:
  • Air, water, and soil monitoring
  • Distributed and low‑cost sensor networks
  • New sensors that unlock previously inaccessible signals
Computational Analytics
Turning data into understanding
We will advance computational methods that integrate physics-based models, scientific AI, and machine learning to extract insight, predict risk, and explore future scenarios at scales relevant to real-world decisions.
Focus areas include:
  • Predictive modeling and simulation
  • Digital twins and integrated system models
  • Trustworthy AI for high‑consequence decisions
Decision Support
Putting science to work
Our ultimate goal is impact. This technical area closes the loop by transforming research into decision-support tools, commercial products, and public services that communities and industries can rely on.
Focus areas include:
  • Operational decision‑support tools
  • Technology commercialization
  • Co‑creation with end users to ensure relevance and adoption

From discovery to deployment

Each ASCEND R&D program drives commercialization through two pathways: industry consortium models that transition breakthroughs directly into partner operations, and dedicated accelerator cohorts that test and refine commercial products within the program's research infrastructure. The Engine provides startups with dedicated advisory support, pilot customer introductions, investor connections, and more.
Commercialization support
Program-Specific Accelerators

Paired with each flagship R&D program, accelerator participants gain direct access to the R&D program’s enabling infrastructure, research teams, and pilot environments.

CEO Matching

A technology-to-CEO matching program that pairs promising R&D projects with experienced executives to form new startup companies.

Venture Capital

Innosphere will launch an ASCEND-aligned venture fund to address the capital gap in the region. Innosphere Fund III, targeted $100M, is a regional fund targeting advanced industries in ASCEND technologies and other key U.S. technologies.

Open Innovation

The ASCEND Engine will engage its corporate partners' open innovation programs to identify areas of strategic focus and intersection with ASCEND technologies and Engine use cases.

Scaleup Program

A new stage-specific scaleup program to serve companies that have graduated beyond the accelerator stage and require targeted support for later-stage commercialization.

Commercialization POstdoc

Postdoctoral fellows interested in commercializing breakthrough technologies from their lab can apply to receive financial support and mentorship from the ASCEND Engine.

Workforce development

The ASCEND Engine’s workforce development strategy is designed to solve the shortage of skilled talent needed to support next‑generation environmental sensing, data, and decision‑making technologies across Colorado and Wyoming. By aligning education, training, and employer demand, the ASCEND Engine is strengthening regional community resilience while expanding economic opportunities.
K–12 STEM engagement
Impacting 6000+ students annually
Early investments through mobile learning labs, robotics and drone programs introduce thousands of students annually to real‑world environmental technologies. These experiences build early awareness, spark career interest, and lay the foundation for long‑term participation in high‑demand fields.
Non-degreed pathways
Upskilling partnerships serving 100+ non-degreed workers per year
Using the gener8tor Skills Accelerator, adults and emerging professionals have access to upskilling. Programs are co‑designed with employers and workforce agencies to ensure training leads directly to jobs, wage gains, and long‑term retention — creating immediate value for both workers and regional industries.
Post-secondary level
Community college and university internships and skills competitions
Addresses critical talent gaps by offering subsidized internships in ASCEND-focused and systems engineering fields. Also supports learning-intensive competitions building in-demand skills in cybersecurity and augmented reality, preparing students to fill essential roles in advanced computation and AI.  

Get Involved

Industry or Philthropic Leader
Gain access to cutting-edge technology by co-investing in ARID, SHIELD, or future R&D programs through industry consortium models. Serve as an Industry Champion advising on strategy and connecting the ASCEND Engine to your networks. Sponsor workforce internships, apprenticeships, and hackathons. Engage in open innovation with portfolio companies and define in-demand skills as a member of a workforce advisory group.
Investors
Early-stage investment opportunities through ASCEND-aligned venture funds. Access a curated pipeline of deep-tech startups with a target of $166M in follow-on venture capital by 2028. Participate in Investor Forums and accelerator demo days. Refer companies to the ASCEND Engine and connect founders to potential customers and strategic partners.
Entrepreneurs and Researchers
Turn your ideas into impact by participating in an ASCEND Engine accelerator aligned with our flagship R&D programs. Apply for access to mentorship, funding, and high-performance computing. Compete for the XPRIZE Moonshot Prize, and participate in hackathons and innovation events. Opportunities exist for CEO-matching and commercialization post-doctoral opportunities. 

Whether you represent a corporation, government agency, foundation, investor, startup, or research institution, there is a meaningful role for you in the ASCEND ecosystem.

Contact Us

Get involved

The ASCEND Engine’s strategy is grounded in active partnerships with leading research institutions, federal laboratories, technology companies, and public-sector agencies across our region.

Talk to our Partnership Director Emily Wilson.

Contact Emily