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Colorado Competitiveness Blog Series: Inside Colorado’s Innovation Ecosystem

Innosphere’s Life Science Accelerator 2025 Cohort Graduation

Did you know that Colorado has the nation’s largest concentration of federal labs outside Washington, D.C? This, along with our world-class universities, skilled workforce, and high standards of living, makes Colorado’s Front Range one of the nation’s most dynamic emerging innovation hubs.

Did you know that Colorado has the nation’s largest concentration of federal labs outside Washington, D.C? This, along with our world-class universities, skilled workforce, and high standards of living, makes Colorado’s Front Range one of the nation’s most dynamic emerging innovation hubs.  

Innosphere’s new Colorado Competitiveness Blog Series dives into the findings of our Comparative Competitiveness Assessment, exploring how the Front Range stacks up against Atlanta, the Twin Cities, and North Carolina’s Research Triangle in critical areas like talent and workforce, venture capital funding, and state support.

“Colorado has demonstrated one of the strongest economies over the medium-term horizon. Though,over the short term, Colorado’s performance has slippedin the rankings, demonstrating the difficulty in maintaining growth for a sustained period of time.”​

– 2025 Colorado Business Economic Outlook

Explore the full Comparative Competitiveness Assessment presentation here.

About Innosphere

For 28 years, Innosphere has been at the forefront of Colorado’s science and technology ecosystem. We’ve helped transform groundbreaking ideas into thriving businesses through comprehensive incubation programs that fuel entrepreneurship and innovation across the region.

Colorado’s Advanced Industries: Anchoring National Competitiveness

In this series, we will look at how Innosphere has worked to amplify and leverage Colorado’s competitive advantages to help establish the state as a leader in advanced industries. Advanced industries are the backbone of innovation and economic resilience. In Colorado, these sectors include:

  • Aerospace & Space
  • Biosciences
  • Advanced Manufacturing
  • Electronics & Quantum
  • Energy & Natural Resources
  • Infrastructure Engineering
  • Technology & Information

These industries don’t just create jobs—they drive national competitiveness and position Colorado as a leader in turning research into real-world impact.

Building Colorado’s Innovation Ecosystem

Driving growth in advanced industries isn’t just about individual companies—it requires a connected, statewide innovation ecosystem powered by funding, expertise, talent, and industry collaboration. To achieve this, Innosphere has implemented a regional strategy designed to:

  • Connect: Forge cross-sector partnerships that tackle shared challenges and accelerate innovation.
  • Orient: Align stakeholders around a unified vision and clear priorities for Colorado’s future.
  • Activate: Deliver targeted programs, resources, and funding to turn ideas into market-ready solutions.
  • Integrate: Coordinate efforts across research institutions, industry leaders, and government to create one cohesive system.

These initiatives, combined with Colorado’s robust venture capital network and thriving accelerator community, position the Front Range as a national model for commercializing cutting-edge research into real-world impact—driving economic growth, strengthening competitiveness, and building a more resilient future for the Rocky Mountain region.

What to Expect in This Series

Over the coming weeks, we will explore:

  • Colorado’s advanced industries and how they compare nationally
  • Research and workforce advantages that set our region apart
  • Why Colorado is the ideal place to grow advanced industries  

Join the Conversation

Be part of shaping Colorado’s innovation future:

  • Subscribe to our newsletter at the bottom of this page for updates
  • Follow us on LinkedIn
  • Share your questions and ideas—what topics matter most to you as we build a stronger, more resilient ecosystem?
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